BDBM50321942 CHEMBL4170773

SMILES Nc1oncc1-c1ccc(F)cc1

InChI Key InChIKey=CQLJZWKEWDVHRN-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50321942   

TargetTryptophan 2,3-dioxygenase(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50321942(CHEMBL4170773)
Affinity DataIC50: 580nMAssay Description:Inhibition of recombinant human TDO2 assessed as decrease in conversion of L-tryptophan to N-formylkynurenine preincubated for 5 mins followed by 0.2...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50321942(CHEMBL4170773)
Affinity DataEC50:  210nMAssay Description:Inhibition of TDO2 in human SW48 cells assessed as decrease in conversion of tryptophan to N-formylkynurenine after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed