BDBM50321180 CHEMBL1163899::rac-3-(4-Nitrophenylamino)-3-(4-(trifluoromethyl)phenyl)-1-(4-methoxyphenyl)propan-1-one

SMILES COc1ccc(cc1)C(=O)CC(Nc1ccc(cc1)[N+]([O-])=O)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=JOCQGPAPUMPYTP-UHFFFAOYSA-N

Data  2 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50321180   

TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321180(rac-3-(4-Nitrophenylamino)-3-(4-(trifluoromethyl)p...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human progesterone receptor B expressed in african green monkey CV1 cells co-transfected with MMTV-Luc after 24 hrs by luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321180(rac-3-(4-Nitrophenylamino)-3-(4-(trifluoromethyl)p...)
Affinity DataIC50: 2.70E+3nMAssay Description:Antagonist activity at human progesterone receptor B expressed in african green monkey CV1 cells co-transfected with MMTV-Luc assessed as effect on p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321180(rac-3-(4-Nitrophenylamino)-3-(4-(trifluoromethyl)p...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]progesterone from human progesterone receptor B after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321180(rac-3-(4-Nitrophenylamino)-3-(4-(trifluoromethyl)p...)
Affinity DataKi:  320nMAssay Description:Displacement of [3H]DHT from human androgen receptor after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed