BDBM50321036 CHEMBL4160447

SMILES C[C@H](Oc1cccc(c1)-c1cccc(c1)-n1ncc(C(O)=O)c1[C@@H]1C[C@H]1c1cn(C)nn1)C1CCCCC1

InChI Key InChIKey=VZVCHNYRESPRBX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50321036   

TargetNuclear factor erythroid 2-related factor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50321036(CHEMBL4160447)
Affinity DataIC50: 10nMAssay Description:Inhibition of full length Flag/His-tagged Keap1 kelch domain (unknown origin)/full length Avi-tagged Nrf2 (unknown origin) interaction after 2.25 hrs...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50321036(CHEMBL4160447)
Affinity DataIC50: 10nMAssay Description:Inhibition of Keap1 kelch domain (unknow origin)/Nrf2-ETGE peptide (unknown origin) interaction by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKelch-like ECH-associated protein 1(Human)
Taizhou University

Curated by ChEMBL
LigandPNGBDBM50321036(CHEMBL4160447)
Affinity DataIC50: 10nMAssay Description:Inhibition of human Keap1-Nrf2 protein-protein interaction by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed