BDBM50320713 5-(4-Dimethylaminomethylenaminosulfonylbenzoyl)-2-{3-[3-fluoro-5-(4-methoxytetrahydro-4H-4-pyranyl)phenoxy]propyl}-8-methoxy-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indolehydrochloride::CHEMBL1163222

SMILES COc1ccc2n(C(=O)c3ccc(cc3)S(=O)(=O)\N=C\N(C)C)c3CCN(CCCOc4cc(F)cc(c4)C4(CCOCC4)OC)Cc3c2c1

InChI Key InChIKey=LMXWOFBYQJEMSP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50320713   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50320713(5-(4-Dimethylaminomethylenaminosulfonylbenzoyl)-2-...)
Affinity DataIC50: 8.14E+4nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood assessed as inhibition of 5-hydroxyeicosatetraenoic acid production by HPLC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed