BDBM50320708 5-(3-Fluorobenzoyl)-2-{3-[3-fluoro-5-(4-methoxytetrahydro-4H-4-pyranyl)phenoxy]propyl}-8-methoxy-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole hydrochloride::CHEMBL1164950

SMILES COc1ccc2n(C(=O)c3cccc(F)c3)c3CCN(CCCOc4cc(F)cc(c4)C4(CCOCC4)OC)Cc3c2c1

InChI Key InChIKey=JZAYARPHTUBBFJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50320708   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50320708(5-(3-Fluorobenzoyl)-2-{3-[3-fluoro-5-(4-methoxytet...)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood assessed as inhibition of LTB4 production by HPLC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50320708(5-(3-Fluorobenzoyl)-2-{3-[3-fluoro-5-(4-methoxytet...)
Affinity DataIC50: 4.05E+4nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood assessed as inhibition of 5-hydroxyeicosatetraenoic acid production by HPLC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50320708(5-(3-Fluorobenzoyl)-2-{3-[3-fluoro-5-(4-methoxytet...)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of 12-hydroxyheptadecatrienoic acid production by HPLC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50320708(5-(3-Fluorobenzoyl)-2-{3-[3-fluoro-5-(4-methoxytet...)
Affinity DataIC50: 3.57E+5nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of 12-hydroxyheptadecatrienoic acid production by HPLC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed