BDBM50320102 1-(2-((5-methoxy-1H-indol-3-yl)methylene)-3-oxo-2,3-dihydrobenzofuran-5-yl)-3-(4-(4-methylpiperazine-1-carbonyl)phenyl)urea::CHEMBL1082622

SMILES COc1ccc2[nH]cc(\C=C3\Oc4ccc(NC(=O)Nc5ccc(cc5)C(=O)N5CCN(C)CC5)cc4C3=O)c2c1

InChI Key InChIKey=BIAXGJMYDHOWPN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50320102   

LigandPNGBDBM50320102(1-(2-((5-methoxy-1H-indol-3-yl)methylene)-3-oxo-2,...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50320102(1-(2-((5-methoxy-1H-indol-3-yl)methylene)-3-oxo-2,...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed