BDBM50319983 3-(pyridin-4-yl)-N-(2-(trifluoromethoxy)benzyl)pyrrolidine-1-carboxamide::CHEMBL1085745

SMILES FC(F)(F)Oc1ccccc1CNC(=O)N1CCC(C1)c1ccncc1

InChI Key InChIKey=QCMYNIHAZUWGBC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50319983   

TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319983(3-(pyridin-4-yl)-N-(2-(trifluoromethoxy)benzyl)pyr...)
Affinity DataIC50: 76nMAssay Description:Inhibition of human soluble epoxide hydrolase assessed as [2-3H]trans-1,3-diphenyl propylene oxide hydrolysis by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319983(3-(pyridin-4-yl)-N-(2-(trifluoromethoxy)benzyl)pyr...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCytochrome P450 2J2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319983(3-(pyridin-4-yl)-N-(2-(trifluoromethoxy)benzyl)pyr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2J2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319983(3-(pyridin-4-yl)-N-(2-(trifluoromethoxy)benzyl)pyr...)
Affinity DataIC50: 300nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCytochrome P450 2J2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319983(3-(pyridin-4-yl)-N-(2-(trifluoromethoxy)benzyl)pyr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2J2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319983(3-(pyridin-4-yl)-N-(2-(trifluoromethoxy)benzyl)pyr...)
Affinity DataIC50: 300nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed