BDBM50319636 CHEMBL1084107::N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6-yl)-2-(dimethylamino)-2-phenylacetamide

SMILES CN(C)C(C(=O)Nc1cc2cc[nH]c(=O)c2cc1Cl)c1ccccc1

InChI Key InChIKey=SWUSXUHTTZKEQG-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50319636   

TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319636(N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6-yl)-2-(...)
Affinity DataIC50: 19nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMyotonin-protein kinase(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319636(N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6-yl)-2-(...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of DMPKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319636(N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6-yl)-2-(...)
Affinity DataIC50: 26nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRho-associated protein kinase 1(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319636(N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6-yl)-2-(...)
Affinity DataIC50: 19nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C epsilon type(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319636(N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6-yl)-2-(...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of PrkceMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCell division control protein 42 homolog(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319636(N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6-yl)-2-(...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of CDc42More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase N2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319636(N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6-yl)-2-(...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of Prkcl2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed