BDBM50319294 (+/-)-5-fluoro-4-methyl-2-(2-methyl-4-(3-(3-methyl-3,6-diazabicyclo[3.1.0]hexan-6-yl)propoxy)phenyl)-1H-benzo[d]imidazole::CHEMBL1086085

SMILES CN1CC2C(C1)N2CCCOc1ccc(-c2nc3ccc(F)c(C)c3[nH]2)c(C)c1

InChI Key InChIKey=VVCHINSCYNDMKE-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50319294   

TargetHistamine H4 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50319294((+/-)-5-fluoro-4-methyl-2-(2-methyl-4-(3-(3-methyl...)
Affinity DataEC50:  710nMAssay Description:Agonist activity at human histamine H4 receptor in SK-N-MC cells assessed as forskolin-stimulated cAMP release preincubated for 10 mins before forsko...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50319294((+/-)-5-fluoro-4-methyl-2-(2-methyl-4-(3-(3-methyl...)
Affinity DataKi:  77nMAssay Description:Displacement of [3H]histamine from human recombinant histamine H4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed