BDBM50318923 2-(3,5-bis(trifluoromethyl)phenyl)-N-(4-(2-chlorophenyl)-6-((R)-2-(hydroxymethyl)pyrrolidin-1-yl)pyridin-3-yl)-N,2-dimethylpropanamide::CHEMBL1083052

SMILES CN(C(=O)C(C)(C)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1cnc(cc1-c1ccccc1Cl)N1CCC[C@@H]1CO

InChI Key InChIKey=XDFFVHQCALIXPH-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50318923   

TargetSubstance-P receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50318923(2-(3,5-bis(trifluoromethyl)phenyl)-N-(4-(2-chlorop...)
Affinity DataKi:  1.58nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50318923(2-(3,5-bis(trifluoromethyl)phenyl)-N-(4-(2-chlorop...)
Affinity DataKi:  7.27nMAssay Description:Displacement of [3H]SR142801 from human NK3 receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed