BDBM50318559 (1R,2S,3r,4R,5S,6s)-6-[(1-Octyl-1H-1,2,3-triazol-4-yl)methylamino]cyclohexane-1,2,3,4,5-pentaol::CHEMBL1085392

SMILES CCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1

InChI Key InChIKey=GOWXONIFDQHALJ-UHFFFAOYSA-N

Data  1 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50318559   

TargetLysosomal acid glucosylceramidase(Human)
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50318559((1R,2S,3r,4R,5S,6s)-6-[(1-Octyl-1H-1,2,3-triazol-4...)
Affinity DataIC50: 2.25E+3nMpH: 5.2Assay Description:Inhibition of recombinant glucocerebrosidase in McIlvaine buffer at pH 5.2 after 10 mins by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50318559((1R,2S,3r,4R,5S,6s)-6-[(1-Octyl-1H-1,2,3-triazol-4...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of yeast alpha-glucosidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProbable alpha-glucosidase Os06g0675700(Rice)
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50318559((1R,2S,3r,4R,5S,6s)-6-[(1-Octyl-1H-1,2,3-triazol-4...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rice alpha-glucosidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetAlpha-galactosidase(Arabian coffee)
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50318559((1R,2S,3r,4R,5S,6s)-6-[(1-Octyl-1H-1,2,3-triazol-4...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of alpha-galactosidase from coffee beansMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetBeta-galactosidase(Bovine)
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50318559((1R,2S,3r,4R,5S,6s)-6-[(1-Octyl-1H-1,2,3-triazol-4...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine liver beta-galactosidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50318559((1R,2S,3r,4R,5S,6s)-6-[(1-Octyl-1H-1,2,3-triazol-4...)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of recombinant beta-glucocerebrosidase after 10 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50318559((1R,2S,3r,4R,5S,6s)-6-[(1-Octyl-1H-1,2,3-triazol-4...)
Affinity DataIC50: 1.10E+3nMpH: 7.4Assay Description:Inhibition of recombinant beta-glucocerebrosidase at pH 7.4 after 10 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50318559((1R,2S,3r,4R,5S,6s)-6-[(1-Octyl-1H-1,2,3-triazol-4...)
Affinity DataIC50: 1.00E+3nMpH: 5.2Assay Description:Inhibition of recombinant beta-glucocerebrosidase at pH 5.2 after 10 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50318559((1R,2S,3r,4R,5S,6s)-6-[(1-Octyl-1H-1,2,3-triazol-4...)
Affinity DataKi:  1.80E+3nMpH: 5.2Assay Description:Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed