BDBM50318379 (E)-4-fluoro-2-(3-(pyridin-2-ylethynyl)cyclohex-2-enylideneaminooxy)benzonitrile::CHEMBL1097370

SMILES Fc1cc(O\N=C2/CCCC(=C2)C#Cc2ccccn2)ccc1C#N

InChI Key InChIKey=LJRJQJYXJJSYID-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50318379   

TargetMetabotropic glutamate receptor 5(Rat)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50318379((E)-4-fluoro-2-(3-(pyridin-2-ylethynyl)cyclohex-2-...)
Affinity DataKi:  56.1nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat brain P2 membrane after 45 mins by beta countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed