BDBM50318296 (R)-Ethyl 5-Cyano-6-methyl-2-propyl-4-quinolin-4-yl-1,4-dihydropyridine-3-carboxylate::CHEMBL1094797

SMILES CCCC1=C([C@@H](C(C#N)C(C)=N1)c1ccnc2ccccc12)C(=O)OCC

InChI Key InChIKey=LQJIEYFFKBLJFV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50318296   

TargetMineralocorticoid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318296((R)-Ethyl 5-Cyano-6-methyl-2-propyl-4-quinolin-4-y...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at Gal4-fused mineralocorticoid receptor expressed in human HuH7 cells assessed as inhibition of aldosterone-induced receptor act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318296((R)-Ethyl 5-Cyano-6-methyl-2-propyl-4-quinolin-4-y...)
Affinity DataIC50: 31nMAssay Description:Antagonist activity at Gal4-fused mineralocorticoid receptor expressed in human HuH7 cells assessed as inhibition of aldosterone-induced receptor act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318296((R)-Ethyl 5-Cyano-6-methyl-2-propyl-4-quinolin-4-y...)
Affinity DataIC50: 270nMAssay Description:Inhibition of glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318296((R)-Ethyl 5-Cyano-6-methyl-2-propyl-4-quinolin-4-y...)
Affinity DataIC50: 730nMAssay Description:Inhibition of androgen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318296((R)-Ethyl 5-Cyano-6-methyl-2-propyl-4-quinolin-4-y...)
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318296((R)-Ethyl 5-Cyano-6-methyl-2-propyl-4-quinolin-4-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of estrogen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed