BDBM50317214 (2R)-N-(adamantan-2-yl)-1-(2-methylpropyl)pyrrolidine-2-carboxamide::CHEMBL1098130

SMILES CC(C)CN1CCC[C@@H]1C(=O)NC1C2CC3CC(C2)CC1C3

InChI Key InChIKey=PGOYJAUWQHMNDQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50317214   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50317214((2R)-N-(adamantan-2-yl)-1-(2-methylpropyl)pyrrolid...)
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of human 11-beta-HSD1 expressed in HEK293 cells co-transfected with GRE-luciferase after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed