BDBM50316373 Argiotoxin-636::CHEMBL1098240

SMILES [#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6]-c1ccc(-[#8])cc1-[#8]

InChI Key InChIKey=IYXKOVFPNWKUPM-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50316373   

TargetGlutamate receptor 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50316373(Argiotoxin-636 | CHEMBL1098240)
Affinity DataIC50: 350nMAssay Description:Inhibition of recombinant GluA1 receptor flip isoform expressed in Xenopus oocytes assessed as inhibition of 100 uM kainate-induced current by patch ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50316373(Argiotoxin-636 | CHEMBL1098240)
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant GluA3 receptor flip isoform expressed in Xenopus oocytes assessed as inhibition of 100 uM kainate-induced current by patch ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50316373(Argiotoxin-636 | CHEMBL1098240)
Affinity DataIC50: 3.40E+3nMAssay Description:Activity at recombinant GluA1 receptor flop isoform expressed in Xenopus oocytes assessed as effect of 100 uM kainate-induced current by patch clamp ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50316373(Argiotoxin-636 | CHEMBL1098240)
Affinity DataIC50: 350nMAssay Description:Inhibition of GluA1 receptor expressed in Xenopus oocytes assessed as inhibition of 100 uM kainate-induced current by patch clamp electrophysiologica...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50316373(Argiotoxin-636 | CHEMBL1098240)
Affinity DataIC50: 230nMAssay Description:Inhibition of GluA3 receptor expressed in Xenopus oocytes assessed as inhibition of 100 uM kainate-induced current by patch clamp electrophysiologica...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 4(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50316373(Argiotoxin-636 | CHEMBL1098240)
Affinity DataIC50: 430nMAssay Description:Inhibition of GluA4 receptor expressed in Xenopus oocytes assessed as inhibition of 100 uM kainate-induced current by patch clamp electrophysiologica...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 1(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50316373(Argiotoxin-636 | CHEMBL1098240)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of rat recombinant GluA1 receptor flop isoform expressed in Xenopus oocytes assessed as inhibition of 100 uM kainate-induced currentMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50316373(Argiotoxin-636 | CHEMBL1098240)
Affinity DataIC50: 10nMAssay Description:Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 1(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50316373(Argiotoxin-636 | CHEMBL1098240)
Affinity DataIC50: 77nMAssay Description:Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 1(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50316373(Argiotoxin-636 | CHEMBL1098240)
Affinity DataIC50: 135nMAssay Description:Antagonist activity at rat GluA1 receptor expressed in Xenopus oocytes at membrane potential -60 mV by two-electrode voltage-clamp electrophysiology ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50316373(Argiotoxin-636 | CHEMBL1098240)
Affinity DataIC50: 177nMAssay Description:Antagonist activity at rat glutamate N1/2A receptor expressed in Xenopus oocytes at membrane potential -60 mV by two-electrode voltage-clamp electrop...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50316373(Argiotoxin-636 | CHEMBL1098240)
Affinity DataIC50: 74nMAssay Description:Inhibition of rat GluN1/2A expressed in xenopus laevis oocytes assessed as inhibition of glycine-evoked current at membrane potential of -60 mV by vo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 1(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50316373(Argiotoxin-636 | CHEMBL1098240)
Affinity DataIC50: 77nMAssay Description:Inhibition of rat GluA1 expressed in xenopus laevis oocytes assessed as inhibition of glutamate-evoked current at membrane potential of -60 mV by vol...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed