BDBM50315849 2-phenyl-N-(3-(2-phenylcyclopropyl)-1H-indazol-5-yl)acetamide::CHEMBL1090911

SMILES O=C(Cc1ccccc1)Nc1ccc2[nH]nc(C3CC3c3ccccc3)c2c1

InChI Key InChIKey=CIWJUMXZAYFUEI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315849   

TargetAurora kinase B(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315849(2-phenyl-N-(3-(2-phenylcyclopropyl)-1H-indazol-5-y...)
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of GST tagged recombinant Aurora B expressed in Hi-5 cells after 1 hr by TRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAurora kinase A(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315849(2-phenyl-N-(3-(2-phenylcyclopropyl)-1H-indazol-5-y...)
Affinity DataIC50: 640nMAssay Description:Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminescenceMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed