BDBM50315847 CHEMBL1093877::N-(6-methyl-3-(phenylethynyl)-1H-indazol-5-yl)-2-(thiophen-2-yl)acetamide

SMILES Cc1cc2[nH]nc(C#Cc3ccccc3)c2cc1NC(=O)Cc1cccs1

InChI Key InChIKey=HFTUUUTZQAVFBK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315847   

TargetAurora kinase B(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315847(N-(6-methyl-3-(phenylethynyl)-1H-indazol-5-yl)-2-(...)
Affinity DataIC50: 110nMAssay Description:Inhibition of GST tagged recombinant Aurora B expressed in Hi-5 cells after 1 hr by TRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAurora kinase A(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315847(N-(6-methyl-3-(phenylethynyl)-1H-indazol-5-yl)-2-(...)
Affinity DataIC50: 240nMAssay Description:Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminescenceMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed