BDBM50315844 CHEMBL1093879::N-(pyridin-2-ylmethyl)-6-(pyrrolidin-1-yl)-3-styryl-1H-indazol-5-amine

SMILES C(Nc1cc2c(\C=C\c3ccccc3)n[nH]c2cc1N1CCCC1)c1ccccn1

InChI Key InChIKey=AIQJXTOEZSDXHV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315844   

TargetAurora kinase B(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315844(N-(pyridin-2-ylmethyl)-6-(pyrrolidin-1-yl)-3-styry...)
Affinity DataIC50: 130nMAssay Description:Inhibition of GST tagged recombinant Aurora B expressed in Hi-5 cells after 1 hr by TRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAurora kinase A(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315844(N-(pyridin-2-ylmethyl)-6-(pyrrolidin-1-yl)-3-styry...)
Affinity DataIC50: 620nMAssay Description:Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminescenceMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed