BDBM50315835 2-(2,5-dimethoxyphenyl)-N-(6-methyl-3-styryl-1H-indazol-5-yl)acetamide::CHEMBL1091617

SMILES COc1ccc(OC)c(CC(=O)Nc2cc3c(\C=C\c4ccccc4)n[nH]c3cc2C)c1

InChI Key InChIKey=KAHHZLXTLVPZAC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315835   

TargetAurora kinase B(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315835(2-(2,5-dimethoxyphenyl)-N-(6-methyl-3-styryl-1H-in...)
Affinity DataIC50: 180nMAssay Description:Inhibition of GST tagged recombinant Aurora B expressed in Hi-5 cells after 1 hr by TRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAurora kinase A(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315835(2-(2,5-dimethoxyphenyl)-N-(6-methyl-3-styryl-1H-in...)
Affinity DataIC50: 42nMAssay Description:Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminescenceMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed