BDBM50315696 CHEMBL4177101

SMILES Clc1ccc(CCCCn2ccnc2)cc1

InChI Key InChIKey=RBTQGGJTFWBCHX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50315696   

TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50315696(CHEMBL4177101)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HO-2 in Sprague-Dawley albino rat brain microsomes assessed as reduction in bilirubin formation using hemin as substrate after 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2020
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50315696(CHEMBL4177101)
Affinity DataIC50: 500nMAssay Description:Inhibition of HO-1 in Sprague-Dawley albino rat spleen microsomes assessed as reduction in bilirubin formation using hemin as substrate after 60 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2020
Entry Details Article
PubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315696(CHEMBL4177101)
Affinity DataIC50: 6.04E+4nMAssay Description:Inhibition of histidine-tagged Pseudomonas aeruginosa LpxC (1-303) expressed in Escherichia coli BL21 (DE3) using UDP-3-O-(R-3-hydroxydecanoyl)-N-ace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315696(CHEMBL4177101)
Affinity DataIC50: 4.32E+4nMAssay Description:Displacement of (S)-N-(2-(N-(3-biphenyl-4-ylcarboxamido-4-(hydroxyamino)-4-oxobutyl)sulfamoyl)ethyl)-3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed