BDBM50315190 (R)-2-(3-(1-(3-methoxypyrazin-2-yl)ethyl)-1H-inden-2-yl)-N,N-dimethylethanamine::CHEMBL1092597

SMILES COc1nccnc1[C@H](C)C1=C(CCN(C)C)Cc2ccccc12

InChI Key InChIKey=VNNFGZRIODMCIW-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50315190   

TargetCytochrome P450 2D6(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50315190((R)-2-(3-(1-(3-methoxypyrazin-2-yl)ethyl)-1H-inden...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50315190((R)-2-(3-(1-(3-methoxypyrazin-2-yl)ethyl)-1H-inden...)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50315190((R)-2-(3-(1-(3-methoxypyrazin-2-yl)ethyl)-1H-inden...)
Affinity DataKi:  1nMAssay Description:Binding affinity at histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50315190((R)-2-(3-(1-(3-methoxypyrazin-2-yl)ethyl)-1H-inden...)
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of dofetilide from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50315190((R)-2-(3-(1-(3-methoxypyrazin-2-yl)ethyl)-1H-inden...)
Affinity DataKi:  3.70E+3nMAssay Description:Binding affinity at M1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed