BDBM50315093 (R)-1-(4-(4-(3-methylmorpholino)-6-(tetrahydro-2H-pyran-4-yl)-1,3,5-triazin-2-yl)phenyl)-3-(4-(4-methylpiperazine-1-carbonyl)phenyl)urea::CHEMBL1092045

SMILES C[C@@H]1COCCN1c1nc(nc(n1)-c1ccc(NC(=O)Nc2ccc(cc2)C(=O)N2CCN(C)CC2)cc1)C1CCOCC1

InChI Key InChIKey=XACUZCZRNNOQMH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315093   

TargetSerine/threonine-protein kinase mTOR(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315093((R)-1-(4-(4-(3-methylmorpholino)-6-(tetrahydro-2H-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6k-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50315093((R)-1-(4-(4-(3-methylmorpholino)-6-(tetrahydro-2H-...)
Affinity DataIC50: 43nMAssay Description:Inhibition of PI3Kalpha assessed as PIP3 accumulation after 24 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed