BDBM50315060 1-(4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-thiomorpholino-1,3,5-triazin-2-yl)phenyl)-3-(4-(4-methylpiperazin-1-yl)phenyl)urea::CHEMBL1091347

SMILES CN1CCN(CC1)c1ccc(NC(=O)Nc2ccc(cc2)-c2nc(nc(n2)N2CCSCC2)N2C3CCC2COC3)cc1

InChI Key InChIKey=NPYFLTXFUHLLOO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315060   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315060(1-(4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-th...)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315060(1-(4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-th...)
Affinity DataIC50: 592nMAssay Description:Inhibition of PI3Kalpha after 15 to 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed