BDBM50315047 1-(4-(4,6-di(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-1,3,5-triazin-2-yl)phenyl)-3-(4-(4-methylpiperazin-1-yl)phenyl)urea::CHEMBL1088973

SMILES CN1CCN(CC1)c1ccc(NC(=O)Nc2ccc(cc2)-c2nc(nc(n2)N2C3CCC2COC3)N2C3CCC2COC3)cc1

InChI Key InChIKey=HJOMTSHJHSGRKP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50315047   

TargetSerine/threonine-protein kinase mTOR(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315047(1-(4-(4,6-di(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315047(1-(4-(4,6-di(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50315047(1-(4-(4,6-di(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-...)
Affinity DataIC50: 899nMAssay Description:Inhibition of PI3Kalpha after 15 to 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed