BDBM50314608 2-amino-1-methyl-4-(pyridin-4-yl)-4-(3'-(trifluoromethoxy)biphenyl-3-yl)-1H-imidazol-5(4H)-one::CHEMBL1092125

SMILES CN1C(N)=NC(C1=O)(c1ccncc1)c1cccc(c1)-c1cccc(OC(F)(F)F)c1

InChI Key InChIKey=JAKDICIOTSABEG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50314608   

TargetBeta-secretase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314608(2-amino-1-methyl-4-(pyridin-4-yl)-4-(3'-(trifluoro...)
Affinity DataIC50: 250nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314608(2-amino-1-methyl-4-(pyridin-4-yl)-4-(3'-(trifluoro...)
Affinity DataIC50: 140nMAssay Description:Inhibition of BACE2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin D(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314608(2-amino-1-methyl-4-(pyridin-4-yl)-4-(3'-(trifluoro...)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of cathepsin D by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed