BDBM50314601 2-amino-1-methyl-4-(pyridin-4-yl)-4-(3-(thiophen-3-yl)phenyl)-1H-imidazol-5(4H)-one::CHEMBL1091441

SMILES CN1C(N)=NC(C1=O)(c1ccncc1)c1cccc(c1)-c1ccsc1

InChI Key InChIKey=LNJSOHPMNUFUKA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50314601   

TargetBeta-secretase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314601(2-amino-1-methyl-4-(pyridin-4-yl)-4-(3-(thiophen-3...)
Affinity DataIC50: 240nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin D(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314601(2-amino-1-methyl-4-(pyridin-4-yl)-4-(3-(thiophen-3...)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of cathepsin D by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314601(2-amino-1-methyl-4-(pyridin-4-yl)-4-(3-(thiophen-3...)
Affinity DataIC50: 190nMAssay Description:Inhibition of BACE2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed