BDBM50313443 CHEMBL1082249::N-(2-(((2R,4aS,5R,10bS)-9-bromo-7-fluoro-5-phenyl-3,4,4a,5,6,10b-hexahydro-2H-pyrano[3,2-c]quinolin-2-yl)methylamino)ethyl)acetamide

SMILES CC(=O)NCCNC[C@H]1CC[C@H]2[C@@H](Nc3c(F)cc(Br)cc3[C@H]2O1)c1ccccc1

InChI Key InChIKey=PMAGPUQCJLWJIW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313443   

TargetKinesin-like protein KIF11(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50313443(N-(2-(((2R,4aS,5R,10bS)-9-bromo-7-fluoro-5-phenyl-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of ATPase activity of human recombinant EG5 assessed as ATP hydrolysis by pyruvate kinase-lactate dehydrogenase coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed