BDBM50313439 1-((2R,4aS,5R,10bS)-9-tert-butyl-5-(thiophen-2-yl)-3,4,4a,5,6,10b-hexahydro-2H-pyrano[3,2-c]quinolin-2-yl)-N-methylmethanamine::CHEMBL1077227

SMILES CNC[C@H]1CC[C@H]2[C@@H](Nc3ccc(cc3[C@H]2O1)C(C)(C)C)c1cccs1

InChI Key InChIKey=USUYYJVVBRVSEY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313439   

TargetKinesin-like protein KIF11(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50313439(1-((2R,4aS,5R,10bS)-9-tert-butyl-5-(thiophen-2-yl)...)
Affinity DataIC50: 5nMAssay Description:Inhibition of ATPase activity of human recombinant EG5 assessed as ATP hydrolysis by pyruvate kinase-lactate dehydrogenase coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed