BDBM50312529 CHEMBL1088158::N-[5-(Adamantan-1-yl-methoxy)-pentyl]-D-galacto-1-deoxynojirimycin

SMILES OC[C@@H]1[C@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCC12CC3CC(CC(C3)C1)C2

InChI Key InChIKey=XVYLNHVEAOOEGI-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50312529   

TargetSucrase-isomaltase, intestinal(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312529(N-[5-(Adamantan-1-yl-methoxy)-pentyl]-D-galacto-1-...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of sucrase by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312529(N-[5-(Adamantan-1-yl-methoxy)-pentyl]-D-galacto-1-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of GBA2 by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312529(N-[5-(Adamantan-1-yl-methoxy)-pentyl]-D-galacto-1-...)
Affinity DataIC50: 500nMAssay Description:Inhibition of glucosylceramide synthase (unknown origin) assessed as catabolism of NBD-glucosylceramideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2016
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312529(N-[5-(Adamantan-1-yl-methoxy)-pentyl]-D-galacto-1-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of GBA1 (unknown origin) using beta-D-[1-14C]glucocerebroside assessed as 4-methylumbelliferrone by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2016
Entry Details Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312529(N-[5-(Adamantan-1-yl-methoxy)-pentyl]-D-galacto-1-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2016
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312529(N-[5-(Adamantan-1-yl-methoxy)-pentyl]-D-galacto-1-...)
Affinity DataIC50: 500nMAssay Description:Inhibition of GCS by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetLactase/phlorizin hydrolase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312529(N-[5-(Adamantan-1-yl-methoxy)-pentyl]-D-galacto-1-...)
Affinity DataIC50: 3.75E+5nMAssay Description:Inhibition of lactase by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312529(N-[5-(Adamantan-1-yl-methoxy)-pentyl]-D-galacto-1-...)
Affinity DataIC50: 500nMAssay Description:Inhibition of lysosomal alpha-glucosidase by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGlycogen debranching enzyme(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312529(N-[5-(Adamantan-1-yl-methoxy)-pentyl]-D-galacto-1-...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of glycogen glycogen de-branching enzyme by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMaltase-glucoamylase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312529(N-[5-(Adamantan-1-yl-methoxy)-pentyl]-D-galacto-1-...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of maltase by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed