BDBM50311288 CHEMBL1078785::N-(2-chlorophenyl)pyrazolo[1,5-a]pyridine-3-carboxamide

SMILES Clc1ccccc1NC(=O)c1cnn2ccccc12

InChI Key InChIKey=CPQRFZBWMKEHSA-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50311288   

TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311288(N-(2-chlorophenyl)pyrazolo[1,5-a]pyridine-3-carbox...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50311288(N-(2-chlorophenyl)pyrazolo[1,5-a]pyridine-3-carbox...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of full length RIPK2 (unknown origin) pretreated for 30 mins followed by ATP addition measured after 2 hrs by ADP-d2 tracer based fluoresc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase Lck(Human)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50311288(N-(2-chlorophenyl)pyrazolo[1,5-a]pyridine-3-carbox...)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed