BDBM50310940 3-bromo-6-tert-butyl-10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4]triazolo[1,5-d][1,4]diazepine::CHEMBL1080396

SMILES Cc1ncn-2c1Cn1nc(nc1-c1cc(Br)ccc-21)C(C)(C)C

InChI Key InChIKey=SQKPTEWYIPLZTB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50310940   

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310940(3-bromo-6-tert-butyl-10-methyl-9H-benzo[f]imidazo[...)
Affinity DataKi:  146nMAssay Description:Displacement of [3H]flumazenil from GABAA alpha-5-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310940(3-bromo-6-tert-butyl-10-methyl-9H-benzo[f]imidazo[...)
Affinity DataKi:  1.07E+3nMAssay Description:Displacement of [3H]flumazenil from GABAA alpha-2-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandPNGBDBM50310940(3-bromo-6-tert-butyl-10-methyl-9H-benzo[f]imidazo[...)
Affinity DataKi:  1.21E+3nMAssay Description:Displacement of [3H]flumazenil from GABAA alpha-3-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandPNGBDBM50310940(3-bromo-6-tert-butyl-10-methyl-9H-benzo[f]imidazo[...)
Affinity DataKi:  3.16E+3nMAssay Description:Displacement of [3H]flumazenil from GABAA alpha-1-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed