BDBM50310149 2-amino-4-(biphenyl-3-yl)-1-methyl-4-(pyridin-4-yl)-1H-imidazol-5(4H)-one::CHEMBL598876::rac-2-amino-4-(biphenyl-3-yl)-1-methyl-4-(pyridin-4-yl)-1H-imidazol-5(4H)-one

SMILES CN1C(N)=NC(C1=O)(c1ccncc1)c1cccc(c1)-c1ccccc1

InChI Key InChIKey=RDWGKVFCNRXSNW-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50310149   

TargetBeta-secretase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50310149(2-amino-4-(biphenyl-3-yl)-1-methyl-4-(pyridin-4-yl...)
Affinity DataIC50: 130nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50310149(2-amino-4-(biphenyl-3-yl)-1-methyl-4-(pyridin-4-yl...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50310149(2-amino-4-(biphenyl-3-yl)-1-methyl-4-(pyridin-4-yl...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50310149(2-amino-4-(biphenyl-3-yl)-1-methyl-4-(pyridin-4-yl...)
Affinity DataIC50: 140nMAssay Description:Inhibition of BACE2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin D(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50310149(2-amino-4-(biphenyl-3-yl)-1-methyl-4-(pyridin-4-yl...)
Affinity DataIC50: 3.01E+4nMAssay Description:Inhibition of cathepsin D by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin D(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50310149(2-amino-4-(biphenyl-3-yl)-1-methyl-4-(pyridin-4-yl...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human cathepsin D by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50310149(2-amino-4-(biphenyl-3-yl)-1-methyl-4-(pyridin-4-yl...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human BACE2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed