BDBM50309830 2-(2-chlorobenzoyl)-1H-benzo[f]chromen-3(2H)-one::2-(4'-Iodobenzoyl)-1,2-dihydro-benzo[f]chromen-3-one::CHEMBL490905

SMILES Clc1ccccc1C(=O)C1Cc2c(OC1=O)ccc1ccccc21

InChI Key InChIKey=AFEIVIYLCPBBNV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50309830   

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Institute of Psychiatry and Neuroscience of Paris

Curated by ChEMBL
LigandPNGBDBM50309830(2-(2-chlorobenzoyl)-1H-benzo[f]chromen-3(2H)-one |...)
Affinity DataIC50: 8.98E+4nMAssay Description:Inhibition of human recombinant SIRT1 by Flour de Lys assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Institute of Psychiatry and Neuroscience of Paris

Curated by ChEMBL
LigandPNGBDBM50309830(2-(2-chlorobenzoyl)-1H-benzo[f]chromen-3(2H)-one |...)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of human recombinant SIRT2 by Flour de Lys assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Institute of Psychiatry and Neuroscience of Paris

Curated by ChEMBL
LigandPNGBDBM50309830(2-(2-chlorobenzoyl)-1H-benzo[f]chromen-3(2H)-one |...)
Affinity DataIC50: 8.98E+4nMAssay Description:Inhibition of human recombinant SIRT1 expressed in Escherichia coli incubated at 37 degC for 2 hrs by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Institute of Psychiatry and Neuroscience of Paris

Curated by ChEMBL
LigandPNGBDBM50309830(2-(2-chlorobenzoyl)-1H-benzo[f]chromen-3(2H)-one |...)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of human recombinant SIRT2 expressed in Escherichia coli incubated at 37 degC for 2 hrs by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed