BDBM50309658 CHEMBL593709::N-(4-(5-cyano-7-(2-hydroxypropan-2-yl)benzo[d]oxazol-2-yl)phenyl)-2-(o-tolyloxy)acetamide

SMILES Cc1ccccc1OCC(=O)Nc1ccc(cc1)-c1nc2cc(cc(c2o1)C(C)(C)O)C#N

InChI Key InChIKey=DPSYAEWABAXSIW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50309658   

TargetCholesteryl ester transfer protein(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50309658(N-(4-(5-cyano-7-(2-hydroxypropan-2-yl)benzo[d]oxaz...)
Affinity DataIC50: 28nMAssay Description:Inhibition of CETP assessed as cholesteryl ester transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetCholine/ethanolaminephosphotransferase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50309658(N-(4-(5-cyano-7-(2-hydroxypropan-2-yl)benzo[d]oxaz...)
Affinity DataIC50: 28nMAssay Description:inhibition of human CEPT assessed as cholesteryl ester transfer by fluorescence transfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed