BDBM50309478 CHEMBL601514::N-((2S,3S,4R,5R)-5-(2-(2-(1H-imidazol-4-yl)ethylamino)-6-(2,2-diphenylethylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)propionamide

SMILES CCC(=O)N[C@H]1C[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NCC(c3ccccc3)c3ccccc3)nc(NCCc3cnc[nH]3)nc12

InChI Key InChIKey=XEBIBTRFVZVYQI-UHFFFAOYSA-N

Data  1 KI  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50309478   

TargetAdenosine receptor A2a(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50309478(N-((2S,3S,4R,5R)-5-(2-(2-(1H-imidazol-4-yl)ethylam...)
Affinity DataIC50: 5.90nMAssay Description:Agonist activity at adenosine A2A receptor in human neutrophils assessed as inhibition of fMLP-induced reactive oxygen species release by chemilumine...More data for this Ligand-Target Pair
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TargetAdenosine receptor A1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50309478(N-((2S,3S,4R,5R)-5-(2-(2-(1H-imidazol-4-yl)ethylam...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human adenosine A1 receptor expressed in CHO cells by GTPPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50309478(N-((2S,3S,4R,5R)-5-(2-(2-(1H-imidazol-4-yl)ethylam...)
Affinity DataEC50:  139nMAssay Description:Agonist activity at human adenosine A3 receptor expressed in CHO cells by GTPPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2b(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50309478(N-((2S,3S,4R,5R)-5-(2-(2-(1H-imidazol-4-yl)ethylam...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human adenosine A2B receptor expressed in CHO cells assessed as effect on cAMP production by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50309478(N-((2S,3S,4R,5R)-5-(2-(2-(1H-imidazol-4-yl)ethylam...)
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]NECA from human recombinant adenosine A2A receptor expressed in Sf21 cells co-expressing GalphaS2, beta4, gamma2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed