BDBM50309153 (2R,3R)-N-(benzofuran-2-ylmethyl)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide::CHEMBL591774

SMILES O[C@H]([C@@H](O)C(=O)N1CCCC1c1ccccc1)C(=O)NCc1cc2ccccc2o1

InChI Key InChIKey=LRRAUDSVXJEODP-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50309153   

TargetMatrix metalloproteinase-14(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309153((2R,3R)-N-(benzofuran-2-ylmethyl)-2,3-dihydroxy-4-...)
Affinity DataKi:  140nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309153((2R,3R)-N-(benzofuran-2-ylmethyl)-2,3-dihydroxy-4-...)
Affinity DataKi:  160nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309153((2R,3R)-N-(benzofuran-2-ylmethyl)-2,3-dihydroxy-4-...)
Affinity DataKi:  300nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309153((2R,3R)-N-(benzofuran-2-ylmethyl)-2,3-dihydroxy-4-...)
Affinity DataKi:  510nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309153((2R,3R)-N-(benzofuran-2-ylmethyl)-2,3-dihydroxy-4-...)
Affinity DataKi:  734nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309153((2R,3R)-N-(benzofuran-2-ylmethyl)-2,3-dihydroxy-4-...)
Affinity DataKi:  7.70E+3nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309153((2R,3R)-N-(benzofuran-2-ylmethyl)-2,3-dihydroxy-4-...)
Affinity DataKi:  1.87E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMatrilysin(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309153((2R,3R)-N-(benzofuran-2-ylmethyl)-2,3-dihydroxy-4-...)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed