BDBM50309147 (2R,3R)-4-(2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxo-N-(2-(thiophen-2-yl)ethyl)butanamide::CHEMBL590343

SMILES O[C@H]([C@@H](O)C(=O)N1CCCC1c1cccc(Cl)c1)C(=O)NCCc1cccs1

InChI Key InChIKey=LIKQSFURRNSUMR-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50309147   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309147((2R,3R)-4-(2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-...)
Affinity DataKi:  11nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309147((2R,3R)-4-(2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-...)
Affinity DataKi:  29nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309147((2R,3R)-4-(2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-...)
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309147((2R,3R)-4-(2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-...)
Affinity DataKi:  1.70E+4nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309147((2R,3R)-4-(2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-...)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309147((2R,3R)-4-(2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-...)
Affinity DataKi:  3.30E+4nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309147((2R,3R)-4-(2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-...)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMatrilysin(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309147((2R,3R)-4-(2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-...)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309147((2R,3R)-4-(2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-...)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed