BDBM50309132 (2R,3R)-4-(4-(2-chlorophenyl)piperazin-1-yl)-2,3-dihydroxy-4-oxo-N-(2-(thiophen-2-yl)ethyl)butanamide::(2R,3R)-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-4-oxo-N-(2-thiophen-2-ylethyl)butanamide::CHEMBL605764

SMILES c1ccc(c(c1)N2CCN(CC2)C(=O)[C@@H]([C@H](C(=O)NCCc3cccs3)O)O)Cl

InChI Key InChIKey=AZEKZZSSVLIPCQ-UHFFFAOYSA-N

Data  9 KI

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50309132   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309132((2R,3R)-4-(4-(2-chlorophenyl)piperazin-1-yl)-2,3-d...)
Affinity DataKi:  400nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDisintegrin and metalloproteinase domain-containing protein 10(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309132((2R,3R)-4-(4-(2-chlorophenyl)piperazin-1-yl)-2,3-d...)
Affinity DataKi:  400nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309132((2R,3R)-4-(4-(2-chlorophenyl)piperazin-1-yl)-2,3-d...)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309132((2R,3R)-4-(4-(2-chlorophenyl)piperazin-1-yl)-2,3-d...)
Affinity DataKi:  9.00E+3nMAssay Description:Inhibition of MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309132((2R,3R)-4-(4-(2-chlorophenyl)piperazin-1-yl)-2,3-d...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309132((2R,3R)-4-(4-(2-chlorophenyl)piperazin-1-yl)-2,3-d...)
Affinity DataKi: >4.00E+4nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309132((2R,3R)-4-(4-(2-chlorophenyl)piperazin-1-yl)-2,3-d...)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMatrilysin(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309132((2R,3R)-4-(4-(2-chlorophenyl)piperazin-1-yl)-2,3-d...)
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309132((2R,3R)-4-(4-(2-chlorophenyl)piperazin-1-yl)-2,3-d...)
Affinity DataKi: >9.00E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed