BDBM50308958 4-(4-(2-(naphthalen-1-yl)-1,3-dioxoisoindoline-5-carbonyl)phenoxy)benzoic acid::4-(4-(2-(naphthalen-1-yl)-1,3-dioxoisoindoline-6-carbonyl)phenoxy)benzoic acid::CHEMBL409660

SMILES OC(=O)c1ccc(Oc2ccc(cc2)C(=O)c2ccc3C(=O)N(C(=O)c3c2)c2cccc3ccccc23)cc1

InChI Key InChIKey=VHEXJIHEHHNFGH-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50308958   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50308958(4-(4-(2-(naphthalen-1-yl)-1,3-dioxoisoindoline-6-c...)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of autotaxin-mediated pNP-TMP hydrolysis in human MDA-MB-435 cells by amplex red protocolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50308958(4-(4-(2-(naphthalen-1-yl)-1,3-dioxoisoindoline-6-c...)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of autotaxin-mediated FS3 hydrolysis in human MDA-MB-435 cells by amplex red protocolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50308958(4-(4-(2-(naphthalen-1-yl)-1,3-dioxoisoindoline-6-c...)
Affinity DataKi:  5.80E+3nMAssay Description:Mixed-type inhibition of autotaxin-mediated FS3 hydrolysis by Michaelis-Menten analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50308958(4-(4-(2-(naphthalen-1-yl)-1,3-dioxoisoindoline-6-c...)
Affinity DataKi:  3.23E+4nMAssay Description:Mixed-type inhibition of autotaxin-mediated FS3 hydrolysis by Michaelis-Menten analysis for enzyme-substrate complexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed