BDBM50308654 1-(5-Bromo-2-hydroxybenzyl)-1-(4-fluorobenzyl)-3-phenylthiourea::CHEMBL589561

SMILES Oc1c(Br)cccc1CN(Cc1ccc(F)cc1)C(=S)Nc1ccccc1

InChI Key InChIKey=PGLLJXXZDBFPCN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50308654   

TargetEpidermal growth factor receptor(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50308654(1-(5-Bromo-2-hydroxybenzyl)-1-(4-fluorobenzyl)-3-p...)
Affinity DataIC50: 980nMAssay Description:Inhibition of cloned EGFR autophosphorylation expressed in baculovirus-infected Sf9 cells by solid-phase ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50308654(1-(5-Bromo-2-hydroxybenzyl)-1-(4-fluorobenzyl)-3-p...)
Affinity DataIC50: 1.87E+3nMAssay Description:Inhibition of human cloned HER2 autophosphorylation expressed in baculovirus-infected Sf9 cells by solid-phase ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50308654(1-(5-Bromo-2-hydroxybenzyl)-1-(4-fluorobenzyl)-3-p...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of HER2 (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed