BDBM50308523 9-[4',4'-Difluoro-4'-(diethylphosphono)butyl]-9-deazaguanine::CHEMBL601916

SMILES CCOP(=O)(OCC)C(F)(F)CCCc1c[nH]c2c1nc(N)[nH]c2=O

InChI Key InChIKey=BMPLIBROIHLOAE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50308523   

TargetPurine nucleoside phosphorylase(Human)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50308523(9-[4',4'-Difluoro-4'-(diethylphosphono)butyl]-9-de...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human erythrocyte PNP assessed as inhibition of 25 uM 7-methylguanosine phosphorolysis by spectrophotometry in presence of 1 mM inorgan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed