BDBM50307483 (S)-2-azido-N-((S)-1-((S)-3-(3,5-bis(trifluoromethyl)phenyl)-1-((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-ylamino)-1-oxopropan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-3-phenylpropanamide::CHEMBL591777

SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1

InChI Key InChIKey=XPGHVAUYKZIYPM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50307483   

TargetProteasome subunit beta type-1(Human)
Gorlaeus Laboratories

Curated by ChEMBL
LigandPNGBDBM50307483((S)-2-azido-N-((S)-1-((S)-3-(3,5-bis(trifluorometh...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of 26S proteasome beta 1 using nLPnLD as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Gorlaeus Laboratories

Curated by ChEMBL
LigandPNGBDBM50307483((S)-2-azido-N-((S)-1-((S)-3-(3,5-bis(trifluorometh...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of 26S proteasome beta 2 using RLR as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Gorlaeus Laboratories

Curated by ChEMBL
LigandPNGBDBM50307483((S)-2-azido-N-((S)-1-((S)-3-(3,5-bis(trifluorometh...)
Affinity DataIC50: 100nMAssay Description:Inhibition of 26S proteasome beta 5 using LLVY as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed