BDBM50306605 (S)-1,1,1-trifluoro-3-((S)-3-(3-(1,1,2,2-tetrafluoroethoxy)phenyl)-8-(3-(trifluoromethoxy)phenyl)-2H-benzo[b][1,4]oxazin-4(3H)-yl)propan-2-ol::CHEMBL602483

SMILES O[C@@H](CN1[C@H](COc2c1cccc2-c1cccc(OC(F)(F)F)c1)c1cccc(OC(F)(F)C(F)F)c1)C(F)(F)F

InChI Key InChIKey=MOOACFAVSYOZPW-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50306605   

TargetCholesteryl ester transfer protein(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306605((S)-1,1,1-trifluoro-3-((S)-3-(3-(1,1,2,2-tetrafluo...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of cholesteryl ester transfer protein in human plasma by [3H]CE HDL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306605((S)-1,1,1-trifluoro-3-((S)-3-(3-(1,1,2,2-tetrafluo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306605((S)-1,1,1-trifluoro-3-((S)-3-(3-(1,1,2,2-tetrafluo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306605((S)-1,1,1-trifluoro-3-((S)-3-(3-(1,1,2,2-tetrafluo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2C19 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306605((S)-1,1,1-trifluoro-3-((S)-3-(3-(1,1,2,2-tetrafluo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306605((S)-1,1,1-trifluoro-3-((S)-3-(3-(1,1,2,2-tetrafluo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP3A4 muscle isoform in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306605((S)-1,1,1-trifluoro-3-((S)-3-(3-(1,1,2,2-tetrafluo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP3A4 tissue isoform in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306605((S)-1,1,1-trifluoro-3-((S)-3-(3-(1,1,2,2-tetrafluo...)
Affinity DataIC50: 26nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306605((S)-1,1,1-trifluoro-3-((S)-3-(3-(1,1,2,2-tetrafluo...)
Affinity DataIC50: 45nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed