BDBM50306437 11-chloro-12-hydroxy-7-methyl-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphtho[2,1-b]azepine-4-carbaldehyde oxime::CHEMBL604732

SMILES CN1CCc2cc(Cl)c(O)cc2[C@@H]2[C@@H]1CCc1c(CN=O)cccc21

InChI Key InChIKey=HLASJEZHQCWEKD-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50306437   

TargetD(1A) dopamine receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50306437(11-chloro-12-hydroxy-7-methyl-6,6a,7,8,9,13b-hexah...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50306437(11-chloro-12-hydroxy-7-methyl-6,6a,7,8,9,13b-hexah...)
Affinity DataKi:  3.30nMAssay Description:Displacement of radioligand from dopamine D5 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50306437(11-chloro-12-hydroxy-7-methyl-6,6a,7,8,9,13b-hexah...)
Affinity DataKi:  882nMAssay Description:Displacement of [3H]methylspiperon from dopamine D2 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50306437(11-chloro-12-hydroxy-7-methyl-6,6a,7,8,9,13b-hexah...)
Affinity DataKi:  4.37E+3nMAssay Description:Displacement of radioligand from dopamine D4 receptor expressed in mouse LTK cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed