BDBM50306417 CHEMBL596621::N-(adamantan-2-yl)-2,3-dihydrospiro[indene-1,4'-piperidine]-1'-carboxamide

SMILES O=C(NC1C2CC3CC(C2)CC1C3)N1CCC2(CCc3ccccc23)CC1

InChI Key InChIKey=LQODPNODUZWIMX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50306417   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50306417(N-(adamantan-2-yl)-2,3-dihydrospiro[indene-1,4'-pi...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in CHO cells assessed as conversion of [3H]cortisone to [3H]cortisol by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50306417(N-(adamantan-2-yl)-2,3-dihydrospiro[indene-1,4'-pi...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of 11beta-HSD1 in human adipocytes assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed