BDBM50305598 1-4-(1H-pyrrol-1-yl)-N-[4-(trifluoromethoxy)phenyl]-piperidinecarboxamide::4-(1H-pyrrol-1-yl)-N-(4-(trifluoromethoxy)phenyl)piperidine-1-carboxamide::CHEMBL590600

SMILES FC(F)(F)Oc1ccc(NC(=O)N2CCC(CC2)n2cccc2)cc1

InChI Key InChIKey=VWASPBPUXCRHTH-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50305598   

TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305598(4-(1H-pyrrol-1-yl)-N-(4-(trifluoromethoxy)phenyl)p...)
Affinity DataIC50: 11nMAssay Description:Displacement of rhodamine-labeled probe from human soluble epoxide hydrolase by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305598(4-(1H-pyrrol-1-yl)-N-(4-(trifluoromethoxy)phenyl)p...)
Affinity DataIC50: 11nMAssay Description:Displacement of rhodamine-labeled probe from rat soluble epoxide hydrolase by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305598(4-(1H-pyrrol-1-yl)-N-(4-(trifluoromethoxy)phenyl)p...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C19(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305598(4-(1H-pyrrol-1-yl)-N-(4-(trifluoromethoxy)phenyl)p...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305598(4-(1H-pyrrol-1-yl)-N-(4-(trifluoromethoxy)phenyl)p...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305598(4-(1H-pyrrol-1-yl)-N-(4-(trifluoromethoxy)phenyl)p...)
Affinity DataIC50: 11nMAssay Description:Inhibition of rat soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305598(4-(1H-pyrrol-1-yl)-N-(4-(trifluoromethoxy)phenyl)p...)
Affinity DataIC50: 126nMAssay Description:Inhibition of human soluble epoxide hydrolase assessed as [2-3H]trans-1,3-diphenyl propylene oxide hydrolysis by cellular assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed