BDBM50305557 CHEMBL611631::N-(5-bromothiazol-2-ylcarbamoyl)-4-(6-fluoropyridin-3-yl)-3-methylbenzenesulfonamide

SMILES Cc1cc(ccc1-c1ccc(F)nc1)S(=O)(=O)NC(=O)Nc1ncc(Br)s1

InChI Key InChIKey=MGILTQRFNXGDIM-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50305557   

TargetFructose-1,6-bisphosphatase 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305557(N-(5-bromothiazol-2-ylcarbamoyl)-4-(6-fluoropyridi...)
Affinity DataIC50: 130nMAssay Description:Inhibition of FBPase in human liverMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305557(N-(5-bromothiazol-2-ylcarbamoyl)-4-(6-fluoropyridi...)
Affinity DataIC50: 90nMAssay Description:Inhibition of FBPase in human liver using fructose-2,6phosphate as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305557(N-(5-bromothiazol-2-ylcarbamoyl)-4-(6-fluoropyridi...)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed