BDBM50305551 1-(4-(4-(3,6-dihydro-2H-pyran-4-yl)thieno[3,2-d]pyrimidin-2-yl)phenyl)-3-ethylurea::CHEMBL600447

SMILES CCNC(=O)Nc1ccc(cc1)-c1nc(C2=CCOCC2)c2sccc2n1

InChI Key InChIKey=IPWXWKUTJBMKOZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50305551   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305551(1-(4-(4-(3,6-dihydro-2H-pyran-4-yl)thieno[3,2-d]py...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of mTOR in HEK293 cells by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50305551(1-(4-(4-(3,6-dihydro-2H-pyran-4-yl)thieno[3,2-d]py...)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of PI3Kalpha by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed