BDBM50305550 3-(1-phenyl-4-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenol::CHEMBL590355

SMILES Oc1cccc(c1)-c1nc(C2CCOCC2)c2cnn(-c3ccccc3)c2n1

InChI Key InChIKey=FWNNYNPGUOAOCU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50305550   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305550(3-(1-phenyl-4-(tetrahydro-2H-pyran-4-yl)-1H-pyrazo...)
Affinity DataIC50: 500nMAssay Description:Inhibition of mTOR in HEK293 cells by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50305550(3-(1-phenyl-4-(tetrahydro-2H-pyran-4-yl)-1H-pyrazo...)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of PI3Kalpha by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed