BDBM50305496 4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline-3-carboximidamide::CHEMBL590586

SMILES CS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(N)=N)c1

InChI Key InChIKey=ORZCTXQPXYCOAF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50305496   

TargetOxysterols receptor LXR-beta(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305496(4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8-(trifluo...)
Affinity DataIC50: 5.13E+3nMAssay Description:Displacement of [3H]TO901317 from human recombinant LXRbeta expressed in Escherichia coli by flashplate methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305496(4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8-(trifluo...)
Affinity DataIC50: 2.99E+4nMAssay Description:Displacement of [3H]TO901317 from human recombinant LXRalpha expressed in Escherichia coli by flashplate methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed